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Hypersensitivity to epirubicin or to any of the excipients, other anthracyclines or anthracenediones.
Lactation.
Intravenous use: persistent myelosuppression; severe hepatic impairment; Myocardiopathy; recent myocardial infarction; severe arrhythmias; previous treatments with maximum cumulative doses of epirubicin and/or other anthracyclines and anthracenediones (see Precautions); patients with acute systemic infections; unstable angina pectoris.
lntravesical use: urinary tract infections; inflammation of the bladder; haematuria; invasive tumours penetrating the bladder; catheterisation problems.
